Sperm motility is lost in vitro as a consequence of mitochondrial free radical production and the generation of electrophilic aldehydes but can be significantly rescued by the presence of nucleophilic thiols
- Creator: Aitken, John R. , Gibb, Zamira , Mitchell, Lisa A. , Lambourne, Sarah R. , Connaughton, Haley S. , De Iuliis, Geoffry N.
- Resource Type: journal article
- Date: 2012
Tyrosine phosphorylation of mouse sperm proteins in a prerequisite for zona pellucida binding: potential involvement of molecular chaperones
- Creator: Asquith, Kelly L. , Nixon, Brett , McLaughlin, Eileen A. , Aitken, John
- Resource Type: conference paper
- Date: 2004
Inhibition of arachidonate 15-lipoxygenase prevents 4-hydroxynonenal-induced protein damage in male germ cells
- Creator: Bromfield, Elizabeth G. , Mihalas, Bettina P. , Dun, Matthew D. , Aitken, R. John , McLaughlin, Eileen A. , Walters, Jessica L. H. , Nixon, Brett
- Resource Type: journal article
- Date: 2017
Chronic testicular Chlamydia muridarum infection impairs mouse fertility and offspring development
- Creator: Bryan, Emily R. , Redgrove, Kate A. , Mooney, Alison R. , Mihalas, Bettina P. , Sutherland, Jessie M. , Carey, Alison J. , Armitage, Charles W. , Trim, Logan K. , Kollipara, Avinash , Mulvey, Peter B. M. , Palframan, Ella , Trollope, Gemma , Bogoevski, Kristofor , McLachlan, Robert , McLaughlin, Eileen A. , Beagley, Kenneth W.
- Resource Type: journal article
- Date: 2020
Hematogenous dissemination of Chlamydia muridarum from the urethra in macrophages causes testicular infection and sperm DNA damage
- Creator: Bryan, Emily R. , Kollipara, Avinash , Trim, Logan K. , Armitage, Charles W. , Carey, Alison J. , Mihalas, Bettina , Redgrove, Kate A. , Mclaughlin, Eileen A. , Beagley, Kenneth W.
- Resource Type: journal article
- Date: 2019
Vaccination protects from chlamydial infertility
- Creator: Bryan, Emily R. , Trim, Logan K. , McLaughlin, Eileen A. , Beagley, Kenneth W. , Sadowski, Pawel , Paramasivan, Selvam , Kim, Jay J. , Gough, Kyle , Worley, Sophia , Maidment, Toby I. , Carey, Alison J. , Mihalas, Bettina
- Resource Type: journal article
- Date: 2023
Maternal smoke exposure impairs the long-term fertility of a female offspring in a murine model
- Creator: Camlin, Nicole J. , Sobinoff, Alexander P. , Sutherland, Jessie M. , Beckett, Emma L. , Jarnicki, Andrew G. , Vanders, Rebecca L. , Hansbro, Philip M. , McLaughlin, Eileen A. , Holt, Janet E.
- Resource Type: journal article
- Date: 2016
Composition of luminal fluid secreted by the seminiferous tubules and after reabsorption by the extratesticular ducts of the Japanese quail, Coturnix coturnix japonica
- Creator: Clulow, J. , Jones, R. C.
- Resource Type: journal article
- Date: 2004
DNA damage in human spermatozoa is highly correlated with the efficiency of chromatin remodeling and the formation of 8-hydroxy-2′-deoxyguanosine, a marker of oxidative stress
- Creator: De Iuliis, Geoffry N. , Thomson, Laura K. , Mitchell, Lisa A. , Finnie, Jane M. , Koppers, Adam John , Hedges, Andrew , Nixon, Brett , Aitken, R. John
- Resource Type: journal article
- Date: 2009
A male-specific role for p38 mitogen-activated protein kinase in germ cell sex differentiation in mice
- Creator: Ewen, Katherine , Jackson, Andrew , Wilhelm, Dagmar , Koopman, Peter
- Resource Type: journal article
- Date: 2010
Transcriptomic profiling of neonatal mouse granulosa cells reveals new insights into primordial follicle activation
- Creator: Ford, Emmalee A. , Frost, Emily R. , Beckett, Emma L. , Roman, Shaun D. , McLaughlin, Eileen A. , Sutherland, Jessie M.
- Resource Type: journal article
- Date: 2022
Neonatal immune activation depletes the ovarian follicle reserve and alters ovarian acute inflammatory mediators in neonatal rats
- Creator: Fuller, Erin A. , Sominsky, Luba , Sutherland, Jessie M. , Redgrove, Kate A. , Harms, Lauren , McLaughlin, Eileen A. , Hodgson, Deborah M.
- Resource Type: journal article
- Date: 2017
L-carnitine and pyruvate are prosurvival factors during the storage of stallion spermatozoa at room temperature
- Creator: Gibb, Zamira , Lambourne, Sarah R. , Quadrelli, Julianne , Smith, Nathan D. , Aitken, Robert J.
- Resource Type: journal article
- Date: 2015
Aldehyde dehydrogenase plays a pivotal role in the maintenance of stallion sperm motility
- Creator: Gibb, Zamira , Lambourne, Sarah R. , Curry, Benjamin J. , Hall, Sally E. , Aitken, Robert J.
- Resource Type: journal article
- Date: 2016
Proteomic analysis of spermatozoa reveals caseins play a pivotal role in preventing short-term periods of subfertility in stallions
- Creator: Griffin, Roisin Ann , Swegen, Aleona , Baker, Mark A. , Ogle, Rachel Ann , Smith, Nathan , Aitken, Robert John , Skerrett-Byrne, David Anthony , Fair, Sean , Gibb, Zamira
- Resource Type: journal article
- Date: 2022
Electrophilic aldehyde products of lipid peroxidation selectively adduct to heat shock protein 90 and arylsulfatase A in stallion spermatozoa
- Creator: Hall, Sally E. , Aitken, R. John , Nixon, Brett , Smith, Nathan D. , Gibb, Zamira
- Resource Type: journal article
- Date: 2017
Heat exposure induces oxidative stress and DNA damage in the male germ line
- Creator: Houston, Brendan J. , Nixon, Brett , Martin, Jacinta H. , De Iuliis, Geoffry N. , Trigg, Natalie A. , Bromfield, Elizabeth G. , McEwan, Kristen E. , Aitken, R. John
- Resource Type: journal article
- Date: 2018
The flagellar protein Enkurin is required for mouse sperm motility and for transport through the female reproductive tract
- Creator: Jungnickel, Melissa K. , Sutton, Keith A. , Baker, Mark A. , Cohen, Michael G. , Sanderson, Michael J. , Florman, Harvey M.
- Resource Type: journal article
- Date: 2018
Chronic acrylamide exposure in male mice results in elevated DNA damage in the germline and heritable induction of CYP2E1 in the testes
- Creator: Katen, Aimee L. , Chambers, Caitlin G. , Nixon, Brett , Roman, Shaun D.
- Resource Type: journal article
- Date: 2016
Epididymal CYP2E1 plays a critical role in acrylamide-induced DNA damage in spermatozoa and paternally mediated embryonic resorptions
- Creator: Katen, Aimee Lee , Sipila, Petra , Mitchell, Lisa A. , Stanger, Simone J. , Nixon, Brett , Roman, Shaun D.
- Resource Type: journal article
- Date: 2017